Hi & Lois probably holds the title for the comic strip most likely to be reprinted in a church bulletin. This is not because it is especially religious, but because it's so damn saccharine that clergy people know that not even the most strident church-lady would ever be offended by it. Thanks to a little digging, though, I think I found one that might come close.
In the first frame we find mom Lois (looking fucking FLY in that tight shirt) and dad Hi (looking like a sack of flour) reminiscing about son Chip and his stubbornness when it came to bath time when he was young. In the next frame, Lois, looking dejected, informs Hi that Chip has done a complete 180 and is now into taking lengthy, record-breaking showers. You can tell by the look on Hi's face that he knows the score. He was a teenage boy himself once. He remembers when he started noticing hair growing where, before, there was none. He remembers the cracking voice and waking up in a puddle of his own ejaculate. You see, if Lois would just turn around and look, she'd understand why Chip's showers have gotten longer. Shit, just look at the smile on his face. Check out the excessive suds around his crotch. You'd have to be blind not to see what's going on! Wake up, Lois, for god's sake! Your son's jerkin' it!
Bonus fact: Did you know that Chip went on to join the army and eventually changed his name to Beetle Bailey? True story.